Description of the Job Duties:

The goal of NIST program in Quantitative Flow Cytometry is to develop reference materials, methodology and procedures to enable quantitative measurements of biological substances such as biological cells, extracellular vesicles, proteins, and nucleic acids. By providing quantitative measurement solutions, we ensure that researchers and clinicians can produce more reliable data, develop better drugs, and provide better treatment to patients in the clinical setting. This individual will support the flow cytometry program under Engineering Biology and Regenerative Medicine by providing assay development and data acquisition and analysis in the area of human adaptive immunity using high-throughput flow cytometry and genomic measurement platform(s). The focus of the work is to probe adaptive immune cells and associated circuitries underlying cell fate decisions and relationship to inflammation caused by infectious diseases, cancer development and therapy.

Federal Employee/Term appointment (U.S. Citizenship required)

  • Advancing cellular imaging – position to be created soon
  • Assay automation – position to be created soon

Prep opportunities: (open to both U.S. and non-US citizen).

Position Title:  Postdoc
Position Description: This project aims to develop novel approaches to evaluate cell count, cell viability, and cell health based on optofluidic kinetic cytometry and complementary automation, microscopy, and advanced cell analysis techniques.  This project is directly applicable to the development and characterization of cell-based therapies and will advance measurement capabilities critical for the success of these novel therapeutics.
Contact: Sumona Sarkar (Sumona.sarkar@nist.gov)

Position Title:  Postdoc
Position Description: In vitro and acellular assays can play an important role in determining the biocompatibility of biomedical products such as dental materials.  This postdoctoral opportunity will feature comprehensive examination of in vitro or other assays relevant to the biocompatibility of dental materials to improve the repeatability, comparability and interlaboratory agreement of the assay results. 
Contact: Elijah Petersen (Elijah.petersen@nist.gov)

Position Title: Biologist for Cell Culture Process Development
Position Description: We are interested in candidates to help to develop bioprocess pipelines to generate cellular starting materials for high-quality cell-based experiments and biological reference materials.  
Contact: John Elliott (Jelliott@nist.gov)

Position Title: Postdoc
Position Description: We are particularly interested in candidates interested in large-scale genotype-phenotype measurements (see example here) or machine-learning approaches to extract useful knowledge from those types of measurements.
Contact: David Ross(david.ross@nist.gov) or Elizabeth Strychalski (elizabeth.strychalski@nist.gov)