Testbed 3: iPSC-derived Cells

A unique challenge in the iPSC-derived cell Test-Bed is the monitoring and control of cell differentiation state during manufacturing. Starting in Year 6, we have expanded the iPSC-derived cardiomyocyte Test-Bed to recognize the importance of other iPSC-derived cells and iPSC-derived products (extracellular vesicles) in response to industry partners’ interests.  Our projects address challenges in iPSC scale and cell differentiation for a variety of iPSC-derived products:

Projects

• iPSC-derived cardiac, neural, and immune cells
• Assessing and Predicting Potency during iPSC Differentiation (Thrust involved 1,2,3)
• Scalable Manufacturing of iPSC-derived Cardiac Cells (Thrust involved 1,2,3)
• Manufacturing iPSC-derived CNS Models and EV Therapeutics (Thrust involved 1,2,3)